Desulfatlon myricatin

Astressin is an amino-terminal truncated analog of CRF that retains high affinity binding to the extracellular domain of the receptor and is believed to act as a neutral competitive antagonist of receptor activation.

SCP1-IN-1 (compoundSH T-62) 是一种针对 SCP1 的强效选择性共价抑制剂。SCP1-IN-1 促进 REST 降解并降低转录活性。高水平的 REST 蛋白驱动一些胶质母细胞瘤细胞的肿瘤生长。SCP1-IN-1 具有研究由 REST 转录活动驱动生长的胶质母细胞瘤的潜力。